Environmental triggers of type 1 diabetes
نویسندگان
چکیده
منابع مشابه
Environmental triggers and determinants of type 1 diabetes.
Type 1 diabetes is perceived as a chronic immune-mediated disease with a subclinical prodromal period characterized by selective loss of insulin-producing beta-cells in the pancreatic islets in genetically susceptible subjects. A series of evidence supports a critical role of exogenous factors in the development of type 1 diabetes, such as 1) the fact that <10% of individuals with HLA-conferred...
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Objective: The role of environmental factors in the development of type1 diabetes mellitus (T1D) is inconclusive. This study aimed to investigate the associations between selected environmental factors and T1D. Materials and Methods: This group matched case-control study included diabetic and healthy subjects younger than 19 years old in 2017. Cases were diabetic subjects diagnosed before the ...
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OBJECTIVE Ljungan virus (LjV) has been proposed as a potential environmental factor for type 1 diabetes. The objective was to test for any association of LjV with type 1 diabetes. RESEARCH DESIGN AND METHODS A nested case-control design was used to test for any association between the development of pre-diabetic autoimmunity and presence of LjV in stool samples (n = 3,803) in the Norwegian En...
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Type 1 diabetes is an autoimmune disease in which the patient's immune system destroys the insulin-secreting beta-cells in the pancreatic islets of Langerhans. A majority of cases is thought to occur as a result of gene-environment interactions. The identity of the environmental factors remains unknown mainly because of the difficulty in linking past exposures with later disease development. Ov...
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ژورنال
عنوان ژورنال: Journal of Paediatrics and Child Health
سال: 2001
ISSN: 1034-4810,1440-1754
DOI: 10.1046/j.1440-1754.2001.00658.x